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MCAM/CD146 Signaling via PLCγ1 Leads to Activation of β(1)-Integrins in Memory T-Cells Resulting in Increased Brain Infiltration
Multiple sclerosis is a chronic auto-inflammatory disease of the central nervous system affecting patients worldwide. Neuroinflammation in multiple sclerosis is mainly driven by peripheral immune cells which invade the central nervous system and cause neurodegenerative inflammation. To enter the tar...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767877/ https://www.ncbi.nlm.nih.gov/pubmed/33381120 http://dx.doi.org/10.3389/fimmu.2020.599936 |