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Comprehensive Analysis of Clinically Significant Hepatitis B Virus Mutations in Relation to Genotype, Subgenotype and Geographic Region

Hepatitis B virus (HBV) is a highly variable DNA virus due to its unique life cycle, which involves an error-prone reverse transcriptase. The high substitution rate drives the evolution of HBV by generating genetic variants upon which selection operates. HBV mutants with clinical implications have b...

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Detalles Bibliográficos
Autores principales:	Araujo, Natalia M., Teles, Sheila A., Spitz, Natália
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7767914/ https://www.ncbi.nlm.nih.gov/pubmed/33381105 http://dx.doi.org/10.3389/fmicb.2020.616023

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