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Development of a marker-free mutagenesis system using CRISPR-Cas9 in the pathogenic mould Aspergillus fumigatus
Aspergillus fumigatus is a saprophytic fungal pathogen that is the cause of more than 300,000 life-threatening infections annually. Our understanding of pathogenesis and factors contributing to disease progression are limited. Development of rapid and versatile gene editing methodologies for A. fumi...
Autores principales: | van Rhijn, Norman, Furukawa, Takanori, Zhao, Can, McCann, Bethany L., Bignell, Elaine, Bromley, Michael J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768092/ https://www.ncbi.nlm.nih.gov/pubmed/33122116 http://dx.doi.org/10.1016/j.fgb.2020.103479 |
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