Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions

Two human induced pluripotent stem cell (hiPSC) lines (UCLi016-A and UCLi017-A) were generated from fibroblast cells of 23- and 34-year-old healthy male donors with no known ocular conditions. Fibroblast cells were derived from skin biopsies and reprogrammed using integration free episomal reprogram...

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Detalles Bibliográficos
Autores principales: Méjécase, Cécile, Harding, Philippa, Sarkar, Hajrah, Eintracht, Jonathan, Lima Cunha, Dulce, Toualbi, Lyes, Moosajee, Mariya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Lab Resource: Multiple Cell Lines
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768179/
https://www.ncbi.nlm.nih.gov/pubmed/33370878
http://dx.doi.org/10.1016/j.scr.2020.102113
Descripción
Sumario:Two human induced pluripotent stem cell (hiPSC) lines (UCLi016-A and UCLi017-A) were generated from fibroblast cells of 23- and 34-year-old healthy male donors with no known ocular conditions. Fibroblast cells were derived from skin biopsies and reprogrammed using integration free episomal reprogramming. The established iPSC lines were found to express pluripotency markers, exhibit differentiation potential in vitro and display a normal karyotype. These cell lines will act as a control lines for researchers studying ocular diseases.

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