Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions

Two human induced pluripotent stem cell (hiPSC) lines (UCLi016-A and UCLi017-A) were generated from fibroblast cells of 23- and 34-year-old healthy male donors with no known ocular conditions. Fibroblast cells were derived from skin biopsies and reprogrammed using integration free episomal reprogram...

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Autores principales: Méjécase, Cécile, Harding, Philippa, Sarkar, Hajrah, Eintracht, Jonathan, Lima Cunha, Dulce, Toualbi, Lyes, Moosajee, Mariya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Lab Resource: Multiple Cell Lines
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768179/
https://www.ncbi.nlm.nih.gov/pubmed/33370878
http://dx.doi.org/10.1016/j.scr.2020.102113
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author Méjécase, Cécile
Harding, Philippa
Sarkar, Hajrah
Eintracht, Jonathan
Lima Cunha, Dulce
Toualbi, Lyes
Moosajee, Mariya
author_facet Méjécase, Cécile
Harding, Philippa
Sarkar, Hajrah
Eintracht, Jonathan
Lima Cunha, Dulce
Toualbi, Lyes
Moosajee, Mariya
author_sort Méjécase, Cécile
collection PubMed
description Two human induced pluripotent stem cell (hiPSC) lines (UCLi016-A and UCLi017-A) were generated from fibroblast cells of 23- and 34-year-old healthy male donors with no known ocular conditions. Fibroblast cells were derived from skin biopsies and reprogrammed using integration free episomal reprogramming. The established iPSC lines were found to express pluripotency markers, exhibit differentiation potential in vitro and display a normal karyotype. These cell lines will act as a control lines for researchers studying ocular diseases.
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spelling pubmed-77681792020-12-30 Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions Méjécase, Cécile Harding, Philippa Sarkar, Hajrah Eintracht, Jonathan Lima Cunha, Dulce Toualbi, Lyes Moosajee, Mariya Stem Cell Res Lab Resource: Multiple Cell Lines Two human induced pluripotent stem cell (hiPSC) lines (UCLi016-A and UCLi017-A) were generated from fibroblast cells of 23- and 34-year-old healthy male donors with no known ocular conditions. Fibroblast cells were derived from skin biopsies and reprogrammed using integration free episomal reprogramming. The established iPSC lines were found to express pluripotency markers, exhibit differentiation potential in vitro and display a normal karyotype. These cell lines will act as a control lines for researchers studying ocular diseases. Elsevier 2020-12 /pmc/articles/PMC7768179/ /pubmed/33370878 http://dx.doi.org/10.1016/j.scr.2020.102113 Text en © 2020 The Author(s) http://creativecommons.org/licenses/by/4.0/ This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Lab Resource: Multiple Cell Lines
Méjécase, Cécile
Harding, Philippa
Sarkar, Hajrah
Eintracht, Jonathan
Lima Cunha, Dulce
Toualbi, Lyes
Moosajee, Mariya
Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions
title Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions
title_full Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions
title_fullStr Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions
title_full_unstemmed Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions
title_short Generation of two human control iPS cell lines (UCLi016-A and UCLi017-A) from healthy donors with no known ocular conditions
title_sort generation of two human control ips cell lines (ucli016-a and ucli017-a) from healthy donors with no known ocular conditions
topic Lab Resource: Multiple Cell Lines
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768179/
https://www.ncbi.nlm.nih.gov/pubmed/33370878
http://dx.doi.org/10.1016/j.scr.2020.102113
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