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Cellular reprogramming to model and study epigenetic alterations in cancer
Although genetic mutations are required for cancer development, reversible non-genetic alterations also play a pivotal role in cancer progression. Failure of well-orchestrated gene regulation by chromatin states and master transcription factors can be one such non-genetic etiology for cancer develop...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768185/ https://www.ncbi.nlm.nih.gov/pubmed/33202305 http://dx.doi.org/10.1016/j.scr.2020.102062 |