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FAM83F regulates canonical Wnt signalling through an interaction with CK1α
The function of the FAM83F protein, like the functions of many members of the FAM83 family, is poorly understood. Here, we show that injection of Fam83f mRNA into Xenopus embryos causes axis duplication, a phenotype indicative of enhanced Wnt signalling. Consistent with this, overexpression of FAM83...
Autores principales: | Dunbar, Karen, Jones, Rebecca A, Dingwell, Kevin, Macartney, Thomas J, Smith, James C, Sapkota, Gopal P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Life Science Alliance LLC
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768192/ https://www.ncbi.nlm.nih.gov/pubmed/33361109 http://dx.doi.org/10.26508/lsa.202000805 |
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