Requirement of DNMT1 to orchestrate epigenomic reprogramming for NPM-ALK–driven lymphomagenesis

Malignant transformation depends on genetic and epigenetic events that result in a burst of deregulated gene expression and chromatin changes. To dissect the sequence of events in this process, we used a T-cell–specific lymphoma model based on the human oncogenic nucleophosmin-anaplastic lymphoma ki...

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Detalles Bibliográficos
Autores principales: Redl, Elisa, Sheibani-Tezerji, Raheleh, Cardona, Crhistian de Jesus, Hamminger, Patricia, Timelthaler, Gerald, Hassler, Melanie Rosalia, Zrimšek, Maša, Lagger, Sabine, Dillinger, Thomas, Hofbauer, Lorena, Draganić, Kristina, Tiefenbacher, Andreas, Kothmayer, Michael, Dietz, Charles H, Ramsahoye, Bernard H, Kenner, Lukas, Bock, Christoph, Seiser, Christian, Ellmeier, Wilfried, Schweikert, Gabriele, Egger, Gerda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768196/
https://www.ncbi.nlm.nih.gov/pubmed/33310759
http://dx.doi.org/10.26508/lsa.202000794

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