Sustained Helicobacter pylori infection accelerates gastric dysplasia in a mouse model

More than 80% of gastric cancer is attributable to stomach infection with Helicobacter pylori (Hp). Gastric preneoplastic progression involves sequential tissue changes, including loss of parietal cells, metaplasia and dysplasia. In transgenic mice, active KRAS expression recapitulates these tissue...

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Detalles Bibliográficos
Autores principales: O’Brien, Valerie P, Koehne, Amanda L, Dubrulle, Julien, Rodriguez, Armando E, Leverich, Christina K, Kong, V Paul, Campbell, Jean S, Pierce, Robert H, Goldenring, James R, Choi, Eunyoung, Salama, Nina R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768197/
https://www.ncbi.nlm.nih.gov/pubmed/33310760
http://dx.doi.org/10.26508/lsa.202000967

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