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Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) membrane (M) protein inhibits type I and III interferon production by targeting RIG-I/MDA-5 signaling

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has quickly spread worldwide and has affected more than 10 million individuals. A typical feature of COVID-19 is the suppression of type I and III interferon (IFN)-mediated antiviral immunity...

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Detalles Bibliográficos
Autores principales: Zheng, Yi, Zhuang, Meng-Wei, Han, Lulu, Zhang, Jing, Nan, Mei-Ling, Zhan, Peng, Kang, Dongwei, Liu, Xinyong, Gao, Chengjiang, Wang, Pei-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768267/
https://www.ncbi.nlm.nih.gov/pubmed/33372174
http://dx.doi.org/10.1038/s41392-020-00438-7