Cargando…

Case Series of Dengue Fever in Peripartum Period: Maternal and Foetal Outcome

Introduction: Dengue fever is a major public health problem in tropical and subtropical areas. There are not many studies concerning the complications of dengue fever in pregnancy. We present four serial cases of dengue fever in pregnancy. Case illustration: Three of four cases were delivered by cae...

Descripción completa

Detalles Bibliográficos
Autores principales: Saroyo, Yudianto Budi, Sungkar, Ali, Irwinda, Rima, Surya, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768497/
https://www.ncbi.nlm.nih.gov/pubmed/33147733
http://dx.doi.org/10.3390/idr12030013
_version_ 1783629170583011328
author Saroyo, Yudianto Budi
Sungkar, Ali
Irwinda, Rima
Surya, Raymond
author_facet Saroyo, Yudianto Budi
Sungkar, Ali
Irwinda, Rima
Surya, Raymond
author_sort Saroyo, Yudianto Budi
collection PubMed
description Introduction: Dengue fever is a major public health problem in tropical and subtropical areas. There are not many studies concerning the complications of dengue fever in pregnancy. We present four serial cases of dengue fever in pregnancy. Case illustration: Three of four cases were delivered by caesarean section; two of them died during post-caesarean care. All cases had the lowest platelet level below 50,000/µL and were given platelet transfusion during and after delivery; they also showed abnormal liver function tests. For foetal outcome, none tested positive for dengue. Discussion: Complication of dengue infection depends on a combination of host and viral virulence. Regardless of prophylactic platelet transfusion, some studies revealed clinical bleeding in patients with dengue infection due to an intricate effect on the haemostatic system. The adverse foetal outcome may contribute because of placental circulation caused by endothelial damage with increased vascular permeability leading to plasma leakage. There is no national guideline for dengue fever in pregnancy. Conclusions: The management of dengue fever in pregnancy at the tertiary hospital is still suboptimal. Dengue fever around peripartum presents a higher risk of morbidity and mortality for the mother and therefore needs a multidiscipline team approach.
format Online
Article
Text
id pubmed-7768497
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-77684972020-12-29 Case Series of Dengue Fever in Peripartum Period: Maternal and Foetal Outcome Saroyo, Yudianto Budi Sungkar, Ali Irwinda, Rima Surya, Raymond Infect Dis Rep Case Report Introduction: Dengue fever is a major public health problem in tropical and subtropical areas. There are not many studies concerning the complications of dengue fever in pregnancy. We present four serial cases of dengue fever in pregnancy. Case illustration: Three of four cases were delivered by caesarean section; two of them died during post-caesarean care. All cases had the lowest platelet level below 50,000/µL and were given platelet transfusion during and after delivery; they also showed abnormal liver function tests. For foetal outcome, none tested positive for dengue. Discussion: Complication of dengue infection depends on a combination of host and viral virulence. Regardless of prophylactic platelet transfusion, some studies revealed clinical bleeding in patients with dengue infection due to an intricate effect on the haemostatic system. The adverse foetal outcome may contribute because of placental circulation caused by endothelial damage with increased vascular permeability leading to plasma leakage. There is no national guideline for dengue fever in pregnancy. Conclusions: The management of dengue fever in pregnancy at the tertiary hospital is still suboptimal. Dengue fever around peripartum presents a higher risk of morbidity and mortality for the mother and therefore needs a multidiscipline team approach. MDPI 2020-11-02 /pmc/articles/PMC7768497/ /pubmed/33147733 http://dx.doi.org/10.3390/idr12030013 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Saroyo, Yudianto Budi
Sungkar, Ali
Irwinda, Rima
Surya, Raymond
Case Series of Dengue Fever in Peripartum Period: Maternal and Foetal Outcome
title Case Series of Dengue Fever in Peripartum Period: Maternal and Foetal Outcome
title_full Case Series of Dengue Fever in Peripartum Period: Maternal and Foetal Outcome
title_fullStr Case Series of Dengue Fever in Peripartum Period: Maternal and Foetal Outcome
title_full_unstemmed Case Series of Dengue Fever in Peripartum Period: Maternal and Foetal Outcome
title_short Case Series of Dengue Fever in Peripartum Period: Maternal and Foetal Outcome
title_sort case series of dengue fever in peripartum period: maternal and foetal outcome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768497/
https://www.ncbi.nlm.nih.gov/pubmed/33147733
http://dx.doi.org/10.3390/idr12030013
work_keys_str_mv AT saroyoyudiantobudi caseseriesofdenguefeverinperipartumperiodmaternalandfoetaloutcome
AT sungkarali caseseriesofdenguefeverinperipartumperiodmaternalandfoetaloutcome
AT irwindarima caseseriesofdenguefeverinperipartumperiodmaternalandfoetaloutcome
AT suryaraymond caseseriesofdenguefeverinperipartumperiodmaternalandfoetaloutcome