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Power and Coherence in the EEG of the Rat: Impact of Behavioral States, Cortical Area, Lateralization and Light/Dark Phases

The sleep-wake cycle is constituted by three behavioral states: wakefulness (W), non-REM (NREM) and REM sleep. These states are associated with drastic changes in cognitive capacities, mostly determined by the function of the thalamo-cortical system, whose activity can be examined by means of intra-...

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Autores principales: Mondino, Alejandra, Cavelli, Matías, González, Joaquín, Osorio, Lucía, Castro-Zaballa, Santiago, Costa, Alicia, Vanini, Giancarlo, Torterolo, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768537/
https://www.ncbi.nlm.nih.gov/pubmed/33317018
http://dx.doi.org/10.3390/clockssleep2040039
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author Mondino, Alejandra
Cavelli, Matías
González, Joaquín
Osorio, Lucía
Castro-Zaballa, Santiago
Costa, Alicia
Vanini, Giancarlo
Torterolo, Pablo
author_facet Mondino, Alejandra
Cavelli, Matías
González, Joaquín
Osorio, Lucía
Castro-Zaballa, Santiago
Costa, Alicia
Vanini, Giancarlo
Torterolo, Pablo
author_sort Mondino, Alejandra
collection PubMed
description The sleep-wake cycle is constituted by three behavioral states: wakefulness (W), non-REM (NREM) and REM sleep. These states are associated with drastic changes in cognitive capacities, mostly determined by the function of the thalamo-cortical system, whose activity can be examined by means of intra-cranial electroencephalogram (iEEG). With the purpose to study in depth the basal activity of the iEEG in adult rats, we analyzed the spectral power and coherence of the iEEG during W and sleep in the paleocortex (olfactory bulb), and in neocortical areas. We also analyzed the laterality of the signals, as well as the influence of the light and dark phases. We found that the iEEG power and coherence of the whole spectrum were largely affected by behavioral states and highly dependent on the cortical areas recorded. We also determined that there are night/day differences in power and coherence during sleep, but not in W. Finally, we observed that, during REM sleep, intra-hemispheric coherence differs between right and left hemispheres. We conclude that the iEEG dynamics are highly dependent on the cortical area and behavioral states. Moreover, there are light/dark phases disparities in the iEEG during sleep, and intra-hemispheric connectivity differs between both hemispheres during REM sleep.
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spelling pubmed-77685372020-12-29 Power and Coherence in the EEG of the Rat: Impact of Behavioral States, Cortical Area, Lateralization and Light/Dark Phases Mondino, Alejandra Cavelli, Matías González, Joaquín Osorio, Lucía Castro-Zaballa, Santiago Costa, Alicia Vanini, Giancarlo Torterolo, Pablo Clocks Sleep Article The sleep-wake cycle is constituted by three behavioral states: wakefulness (W), non-REM (NREM) and REM sleep. These states are associated with drastic changes in cognitive capacities, mostly determined by the function of the thalamo-cortical system, whose activity can be examined by means of intra-cranial electroencephalogram (iEEG). With the purpose to study in depth the basal activity of the iEEG in adult rats, we analyzed the spectral power and coherence of the iEEG during W and sleep in the paleocortex (olfactory bulb), and in neocortical areas. We also analyzed the laterality of the signals, as well as the influence of the light and dark phases. We found that the iEEG power and coherence of the whole spectrum were largely affected by behavioral states and highly dependent on the cortical areas recorded. We also determined that there are night/day differences in power and coherence during sleep, but not in W. Finally, we observed that, during REM sleep, intra-hemispheric coherence differs between right and left hemispheres. We conclude that the iEEG dynamics are highly dependent on the cortical area and behavioral states. Moreover, there are light/dark phases disparities in the iEEG during sleep, and intra-hemispheric connectivity differs between both hemispheres during REM sleep. MDPI 2020-12-09 /pmc/articles/PMC7768537/ /pubmed/33317018 http://dx.doi.org/10.3390/clockssleep2040039 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Mondino, Alejandra
Cavelli, Matías
González, Joaquín
Osorio, Lucía
Castro-Zaballa, Santiago
Costa, Alicia
Vanini, Giancarlo
Torterolo, Pablo
Power and Coherence in the EEG of the Rat: Impact of Behavioral States, Cortical Area, Lateralization and Light/Dark Phases
title Power and Coherence in the EEG of the Rat: Impact of Behavioral States, Cortical Area, Lateralization and Light/Dark Phases
title_full Power and Coherence in the EEG of the Rat: Impact of Behavioral States, Cortical Area, Lateralization and Light/Dark Phases
title_fullStr Power and Coherence in the EEG of the Rat: Impact of Behavioral States, Cortical Area, Lateralization and Light/Dark Phases
title_full_unstemmed Power and Coherence in the EEG of the Rat: Impact of Behavioral States, Cortical Area, Lateralization and Light/Dark Phases
title_short Power and Coherence in the EEG of the Rat: Impact of Behavioral States, Cortical Area, Lateralization and Light/Dark Phases
title_sort power and coherence in the eeg of the rat: impact of behavioral states, cortical area, lateralization and light/dark phases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768537/
https://www.ncbi.nlm.nih.gov/pubmed/33317018
http://dx.doi.org/10.3390/clockssleep2040039
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