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Benchmark of Generic Shapes for Macrocycles
[Image: see text] Macrocycles target proteins that are otherwise considered undruggable because of a lack of hydrophobic cavities and the presence of extended featureless surfaces. Increasing efforts by computational chemists have developed effective software to overcome the restrictions of torsiona...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical
Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768607/ https://www.ncbi.nlm.nih.gov/pubmed/33270455 http://dx.doi.org/10.1021/acs.jcim.0c01038 |