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DIA-based systems biology approach unveils E3 ubiquitin ligase-dependent responses to a metabolic shift

The yeast Saccharomyces cerevisiae is a powerful model system for systems-wide biology screens and large-scale proteomics methods. Nearly complete proteomics coverage has been achieved owing to advances in mass spectrometry. However, it remains challenging to scale this technology for rapid and high...

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Detalles Bibliográficos
Autores principales: Karayel, Ozge, Michaelis, André C., Mann, Matthias, Schulman, Brenda A., Langlois, Christine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768684/
https://www.ncbi.nlm.nih.gov/pubmed/33288721
http://dx.doi.org/10.1073/pnas.2020197117

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