Colorectal Cancer Screening Methods and Molecular Markers for Early Detection

Colorectal cancer (CRC) is one of the most common malignant tumors in the digestive tract in humans. The development of colorectal cancer is composed of multiple stages, starting with benign adenomatous polyps in the inner wall of the large intestine and rectum, and then gradually developing. Then i...

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Detalles Bibliográficos
Autores principales: Wu, Ziwei, Li, You, Zhang, Yibin, Hu, Hui, Wu, Tangwei, Liu, Shuiyi, Chen, Weiqun, Xie, Shenggao, Lu, Zhongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7768867/
https://www.ncbi.nlm.nih.gov/pubmed/33353503
http://dx.doi.org/10.1177/1533033820980426
Descripción
Sumario:Colorectal cancer (CRC) is one of the most common malignant tumors in the digestive tract in humans. The development of colorectal cancer is composed of multiple stages, starting with benign adenomatous polyps in the inner wall of the large intestine and rectum, and then gradually developing. Then it developed into advanced adenomas carcinoma in situ and invasive carcinoma. Represents the distant metastasis of the most advanced development. The purpose of this review is to novel routine screening and diagnostic methods (e.g., Endoscopy and CT colonoscopy, SEPT9 methylation assay, Fecal test) and find reliable molecular markers for early diagnosis of CRC.

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