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ZFP91 is required for the maintenance of regulatory T cell homeostasis and function

Autophagy programs the metabolic and functional fitness of regulatory T (T reg) cells to establish immune tolerance, yet the mechanisms governing autophagy initiation in T reg cells remain unclear. Here, we show that the E3 ubiquitin ligase ZFP91 facilitates autophagy activation to sustain T reg cel...

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Detalles Bibliográficos
Autores principales:	Wang, Aiting, Ding, Lei, Wu, Zhongqiu, Ding, Rui, Teng, Xiao-Lu, Wang, Feixiang, Hu, Zhilin, Chen, Lei, Yu, Xiaoyan, Zou, Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769166/ https://www.ncbi.nlm.nih.gov/pubmed/33355624 http://dx.doi.org/10.1084/jem.20201217

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