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Base editing with high efficiency in allotetraploid oilseed rape by A3A‐PBE system

CRISPR/Cas‐base editing is an emerging technology that could convert a nucleotide to another type at the target site. In this study, A3A‐PBE system consisting of human A3A cytidine deaminase fused with a Cas9 nickase and uracil glycosylase inhibitor was established and developed in allotetraploid Br...

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Detalles Bibliográficos
Autores principales: Cheng, Hongtao, Hao, Mengyu, Ding, Bingli, Mei, Desheng, Wang, Wenxiang, Wang, Hui, Zhou, Rijin, Liu, Jia, Li, Chao, Hu, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769242/
https://www.ncbi.nlm.nih.gov/pubmed/32640102
http://dx.doi.org/10.1111/pbi.13444