The plasticity of the pyruvate dehydrogenase complex confers a labile structure that is associated with its catalytic activity

The pyruvate dehydrogenase complex (PDC) is a multienzyme complex that plays a key role in energy metabolism by converting pyruvate to acetyl-CoA. An increase of nuclear PDC has been shown to be correlated with an increase of histone acetylation that requires acetyl-CoA. PDC has been reported to for...

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Detalles Bibliográficos
Autores principales: Lee, Jaehyoun, Oh, Seunghee, Bhattacharya, Saikat, Zhang, Ying, Florens, Laurence, Washburn, Michael P., Workman, Jerry L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769281/
https://www.ncbi.nlm.nih.gov/pubmed/33370314
http://dx.doi.org/10.1371/journal.pone.0243489

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