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Efficacy of Raman spectroscopy in the diagnosis of hepatocellular carcinoma: A protocol for systematic review and meta-analysis

BACKGROUND: To comprehensively analyze the relative effectiveness of Raman spectroscopy (RS) in the diagnosis of suspected hepatocellular carcinoma (HCC). METHODS: We will perform a complete systematic review based on studies from PubMed/Medline, EMBASE, Web of Science, Ovid, Web of Knowledge, Cochr...

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Detalles Bibliográficos
Autores principales: Jin, Hongyu, Zhang, Man, Jia, Kaiyu, Huang, Libin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769366/
https://www.ncbi.nlm.nih.gov/pubmed/33350784
http://dx.doi.org/10.1097/MD.0000000000023884
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author Jin, Hongyu
Zhang, Man
Jia, Kaiyu
Huang, Libin
author_facet Jin, Hongyu
Zhang, Man
Jia, Kaiyu
Huang, Libin
author_sort Jin, Hongyu
collection PubMed
description BACKGROUND: To comprehensively analyze the relative effectiveness of Raman spectroscopy (RS) in the diagnosis of suspected hepatocellular carcinoma (HCC). METHODS: We will perform a complete systematic review based on studies from PubMed/Medline, EMBASE, Web of Science, Ovid, Web of Knowledge, Cochrane Library and CNKI. We plan to identify over 2000 spectra with strict criteria in several individual studies published between January 2008 and November 2020 in accordance to Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. We are going to summarize the test performance using random effects models. RESULTS: This study will provide solid evidence and data on the sensitivity, specificity and accuracy of RS in the diagnosis of HCC. CONCLUSION: Through this meta-analysis, we intend to provide the pooled sensitivity, specificity and diagnostic accuracy of RS in the diagnosis of suspected HCC. Other parameters like positive LR, negative LR, DOR and AUC of the SROC curve will also be calculated and drawn to help illustrate the efficacy of RS in the diagnosis of HCC.
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spelling pubmed-77693662020-12-29 Efficacy of Raman spectroscopy in the diagnosis of hepatocellular carcinoma: A protocol for systematic review and meta-analysis Jin, Hongyu Zhang, Man Jia, Kaiyu Huang, Libin Medicine (Baltimore) 7100 BACKGROUND: To comprehensively analyze the relative effectiveness of Raman spectroscopy (RS) in the diagnosis of suspected hepatocellular carcinoma (HCC). METHODS: We will perform a complete systematic review based on studies from PubMed/Medline, EMBASE, Web of Science, Ovid, Web of Knowledge, Cochrane Library and CNKI. We plan to identify over 2000 spectra with strict criteria in several individual studies published between January 2008 and November 2020 in accordance to Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines. We are going to summarize the test performance using random effects models. RESULTS: This study will provide solid evidence and data on the sensitivity, specificity and accuracy of RS in the diagnosis of HCC. CONCLUSION: Through this meta-analysis, we intend to provide the pooled sensitivity, specificity and diagnostic accuracy of RS in the diagnosis of suspected HCC. Other parameters like positive LR, negative LR, DOR and AUC of the SROC curve will also be calculated and drawn to help illustrate the efficacy of RS in the diagnosis of HCC. Lippincott Williams & Wilkins 2020-12-24 /pmc/articles/PMC7769366/ /pubmed/33350784 http://dx.doi.org/10.1097/MD.0000000000023884 Text en Copyright © 2020 the Author(s). Published by Wolters Kluwer Health, Inc. http://creativecommons.org/licenses/by/4.0 This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0
spellingShingle 7100
Jin, Hongyu
Zhang, Man
Jia, Kaiyu
Huang, Libin
Efficacy of Raman spectroscopy in the diagnosis of hepatocellular carcinoma: A protocol for systematic review and meta-analysis
title Efficacy of Raman spectroscopy in the diagnosis of hepatocellular carcinoma: A protocol for systematic review and meta-analysis
title_full Efficacy of Raman spectroscopy in the diagnosis of hepatocellular carcinoma: A protocol for systematic review and meta-analysis
title_fullStr Efficacy of Raman spectroscopy in the diagnosis of hepatocellular carcinoma: A protocol for systematic review and meta-analysis
title_full_unstemmed Efficacy of Raman spectroscopy in the diagnosis of hepatocellular carcinoma: A protocol for systematic review and meta-analysis
title_short Efficacy of Raman spectroscopy in the diagnosis of hepatocellular carcinoma: A protocol for systematic review and meta-analysis
title_sort efficacy of raman spectroscopy in the diagnosis of hepatocellular carcinoma: a protocol for systematic review and meta-analysis
topic 7100
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769366/
https://www.ncbi.nlm.nih.gov/pubmed/33350784
http://dx.doi.org/10.1097/MD.0000000000023884
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