Podocyte-specific knockout of the neonatal Fc receptor (FcRn) results in differential protection depending on the model of glomerulonephritis

Podocytes have been proposed to be antigen presenting cells (APCs). In traditional APCs, the neonatal Fc receptor (FcRn) is required for antigen presentation and global knockout of FcRn protects against glomerulonephritis. Since podocytes express FcRn, we sought to determine whether the absence of p...

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Detalles Bibliográficos
Autores principales: Dylewski, James F., Tonsawan, Pantipa, Garcia, Gabriela, Lewis, Linda, Blaine, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769425/
https://www.ncbi.nlm.nih.gov/pubmed/33370294
http://dx.doi.org/10.1371/journal.pone.0230401

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769425/
https://www.ncbi.nlm.nih.gov/pubmed/33370294
http://dx.doi.org/10.1371/journal.pone.0230401

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