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Development of a hybrid model for a partially known intracellular signaling pathway through correction term estimation and neural network modeling
Developing an accurate first-principle model is an important step in employing systems biology approaches to analyze an intracellular signaling pathway. However, an accurate first-principle model is difficult to be developed since it requires in-depth mechanistic understandings of the signaling path...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769624/ https://www.ncbi.nlm.nih.gov/pubmed/33315899 http://dx.doi.org/10.1371/journal.pcbi.1008472 |