The immune system view of the coronavirus SARS-CoV-2

Knowing the “point of view” of the immune system is essential to understand the characteristic of a pandemic, such as that generated by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2, responsible for the Coronavirus Disease (COVID)-19. In this review, we will discuss the general host...

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Autores principales: Celardo, Ivana, Pace, Luigia, Cifaldi, Loredana, Gaudio, Carlo, Barnaba, Vincenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769684/
https://www.ncbi.nlm.nih.gov/pubmed/33371901
http://dx.doi.org/10.1186/s13062-020-00283-2
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author Celardo, Ivana
Pace, Luigia
Cifaldi, Loredana
Gaudio, Carlo
Barnaba, Vincenzo
author_facet Celardo, Ivana
Pace, Luigia
Cifaldi, Loredana
Gaudio, Carlo
Barnaba, Vincenzo
author_sort Celardo, Ivana
collection PubMed
description Knowing the “point of view” of the immune system is essential to understand the characteristic of a pandemic, such as that generated by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2, responsible for the Coronavirus Disease (COVID)-19. In this review, we will discuss the general host/pathogen interactions dictating protective immune response or immunopathology, addressing the role of immunity or immunopathology in influencing the clinical infection outcome, and debate the potential immunoprophylactic and immunotherapy strategies required to fight the virus infection.
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spelling pubmed-77696842020-12-29 The immune system view of the coronavirus SARS-CoV-2 Celardo, Ivana Pace, Luigia Cifaldi, Loredana Gaudio, Carlo Barnaba, Vincenzo Biol Direct Review Knowing the “point of view” of the immune system is essential to understand the characteristic of a pandemic, such as that generated by the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV)-2, responsible for the Coronavirus Disease (COVID)-19. In this review, we will discuss the general host/pathogen interactions dictating protective immune response or immunopathology, addressing the role of immunity or immunopathology in influencing the clinical infection outcome, and debate the potential immunoprophylactic and immunotherapy strategies required to fight the virus infection. BioMed Central 2020-12-29 /pmc/articles/PMC7769684/ /pubmed/33371901 http://dx.doi.org/10.1186/s13062-020-00283-2 Text en © The Author(s) 2021 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Review
Celardo, Ivana
Pace, Luigia
Cifaldi, Loredana
Gaudio, Carlo
Barnaba, Vincenzo
The immune system view of the coronavirus SARS-CoV-2
title The immune system view of the coronavirus SARS-CoV-2
title_full The immune system view of the coronavirus SARS-CoV-2
title_fullStr The immune system view of the coronavirus SARS-CoV-2
title_full_unstemmed The immune system view of the coronavirus SARS-CoV-2
title_short The immune system view of the coronavirus SARS-CoV-2
title_sort immune system view of the coronavirus sars-cov-2
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769684/
https://www.ncbi.nlm.nih.gov/pubmed/33371901
http://dx.doi.org/10.1186/s13062-020-00283-2
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