Cargando…

Structural insights of key enzymes into therapeutic intervention against SARS-CoV-2

COVID-19 pandemic, caused by SARS-CoV-2, has drastically affected human health all over the world. After the emergence of the pandemic the major focus of efforts to attenuate the infection has been on repurposing the already approved drugs to treat COVID-19 adopting a fast-track strategy. However, t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shahid, Munazza, Shahzad-ul-Hussan, Syed
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769706/ https://www.ncbi.nlm.nih.gov/pubmed/33383190 http://dx.doi.org/10.1016/j.jsb.2020.107690

Ejemplares similares

Identification of potential inhibitors of three key enzymes of SARS-CoV2 using computational approach
por: Iftikhar, Hafsa, et al.
Publicado: (2020)

An Engineered Microvirin Variant with Identical Structural Domains Potently Inhibits Human Immunodeficiency Virus and Hepatitis C Virus Cellular Entry
por: Shahid, Munazza, et al.
Publicado: (2020)

SARS-CoV-2: An Update on Genomics, Risk Assessment, Potential Therapeutics and Vaccine Development
por: Mehmood, Iqra, et al.
Publicado: (2021)

New insights on possible vaccine development against SARS-CoV-2
por: Chaudhry, Sundas Nasir, et al.
Publicado: (2020)

Deep learning application detecting SARS-CoV-2 key enzymes inhibitors
por: Benarous, Leila, et al.
Publicado: (2022)

Modulation of IRAK enzymes as a therapeutic strategy against SARS-CoV-2 induced cytokine storm
por: Mahmoud, Ismail Sami, et al.
Publicado: (2023)

Therapeutic and vaccine strategies against SARS-CoV-2: past, present and future
por: Rehman, Mubasher, et al.
Publicado: (2020)

Structural insights into SARS-CoV-2 infection and therapeutics development
por: Sun, Gangyu, et al.
Publicado: (2021)

Household studies provide key insights on the transmission of, and susceptibility to, SARS-CoV-2
por: Pitzer, Virginia E, et al.
Publicado: (2020)

Bioengineered angiotensin-converting-enzyme-2: a potential therapeutic option against SARS-CoV-2 infection
por: Maiti, Biplab K.
Publicado: (2021)

Culinary spice bioactives as potential therapeutics against SARS-CoV-2: Computational investigation
por: Natesh, Jagadish, et al.
Publicado: (2021)

SARS-CoV-2 Myocarditis: Insights Into Incidence, Prognosis, and Therapeutic Implications
por: Abou Hassan, Ossama K., et al.
Publicado: (2021)

Discovering small-molecule therapeutics against SARS-CoV-2
por: Tiwari, Vaibhav, et al.
Publicado: (2020)

Natural therapeutics against SARS CoV2: the potentiality and challenges
por: Bhar, Anirban, et al.
Publicado: (2022)

Point-of-Care Testing—The Key in the Battle against SARS-CoV-2 Pandemic
por: Iliescu, Florina Silvia, et al.
Publicado: (2021)

In-silico studies of inhibitory compounds against protease enzymes of SARS-CoV-2
por: Khan, Saba, et al.
Publicado: (2023)

Unlocking COVID therapeutic targets: A structure-based rationale against SARS-CoV-2, SARS-CoV and MERS-CoV Spike
por: Trigueiro-Louro, João, et al.
Publicado: (2020)

Spike S2 Subunit: The Dark Horse in the Race for Prophylactic and Therapeutic Interventions against SARS-CoV-2
por: Ng, Kim Tien, et al.
Publicado: (2021)

Reverse vaccinology assisted designing of multiepitope-based subunit vaccine against SARS-CoV-2
por: Tahir ul Qamar, Muhammad, et al.
Publicado: (2020)

The emerging SARS-CoV, MERS-CoV, and SARS-CoV-2: An insight into the viruses zoonotic aspects
por: Al-Salihi, Karima A., et al.
Publicado: (2021)

Biochemical features and mutations of key proteins in SARS-CoV-2 and their impacts on RNA therapeutics
por: Zeng, Li, et al.
Publicado: (2021)

Insights into the evolutionary and prophylactic analysis of SARS-CoV-2: A review
por: Akram, Fatima, et al.
Publicado: (2022)

Repurposing of SARS-CoV nucleocapsid protein specific nuclease resistant RNA aptamer for therapeutics against SARS-CoV-2
por: Parashar, Nidarshana Chaturvedi, et al.
Publicado: (2020)

Drug repurposing against SARS-CoV-1, SARS-CoV-2 and MERS-CoV
por: Aherfi, Sarah, et al.
Publicado: (2021)

Key epidemiological drivers and impact of interventions in the 2020 SARS-CoV-2 epidemic in England
por: Knock, Edward S., et al.
Publicado: (2021)

Insight into the Advances in Clinical Trials of SARS-CoV-2 Vaccines
por: Basheeruddin Asdaq, Syed Mohammed, et al.
Publicado: (2022)

Therapeutic significance of nano- and biosensor technology in combating SARS-CoV-2: a review
por: Abid, Rameesha, et al.
Publicado: (2022)

Virtual screening of potential phyto-candidates as therapeutic leads against SARS-CoV-2 infection
por: Dharmashekara, Chandan, et al.
Publicado: (2021)

Enzymatic approaches against SARS-CoV-2 infection with an emphasis on the telomere-associated enzymes
por: Valdiani, Alireza, et al.
Publicado: (2023)

Ebselen, a new candidate therapeutic against SARS-CoV-2
por: Haritha, C.V., et al.
Publicado: (2020)

Repurposing current therapeutic regimens against SARS-CoV-2 (Review)
por: K. Konstantinidou, Sofia, et al.
Publicado: (2020)

Current status of therapeutic monoclonal antibodies against SARS-CoV-2
por: Kumar, Sanjeev, et al.
Publicado: (2021)

Exploration of In-silico screening of therapeutic agents against SARS-CoV-2
por: Thakur, Yamini, et al.
Publicado: (2021)

Breastfeeding importance and its therapeutic potential against SARS‐CoV‐2
por: Vasques da Costa, Aline, et al.
Publicado: (2021)

Significance of Immune Status of SARS-CoV-2 Infected Patients in Determining the Efficacy of Therapeutic Interventions
por: Saratale, Ganesh Dattatraya, et al.
Publicado: (2022)

Combating the challenges of COVID-19 pandemic: Insights into molecular mechanisms, immune responses and therapeutics against SARS-CoV-2
por: Negi, Kriti, et al.
Publicado: (2023)

Mutations in SARS-CoV-2: Insights on structure, variants, vaccines, and biomedical interventions
por: Abulsoud, Ahmed I., et al.
Publicado: (2023)

C(60) fullerene against SARS-CoV-2 coronavirus: an in silico insight
por: Hurmach, Vasyl V., et al.
Publicado: (2021)

Mechanistic insight into the protective and pathogenic immune-responses against SARS-CoV-2
por: Purbey, Prabhat K., et al.
Publicado: (2023)

Structural insights into the effect of mutations in the spike protein of SARS-CoV-2 on the binding with human furin protein
por: Suleman, Muhammad, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_71go2uqkajjrh3u66824fm8nir