Fluoropyrimidine-induced cardiotoxicity

Cardio-oncology is a discipline based on early screening, monitoring, and treating chemotherapy-induced cardiotoxicity. There are many chemotherapeutics known for their cardiac toxic effects, including fluoropyrimidines. Fluoropyrimidine represents the cornerstone of many types of cancer and each ye...

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Autores principales: Deac, Andrada Larisa, Burz, Claudia Cristina, Bocsan, Ioana Corina, Buzoianu, Anca Dana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2020
Materias:
Minireviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769712/
https://www.ncbi.nlm.nih.gov/pubmed/33437663
http://dx.doi.org/10.5306/wjco.v11.i12.1008
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author Deac, Andrada Larisa
Burz, Claudia Cristina
Bocsan, Ioana Corina
Buzoianu, Anca Dana
author_facet Deac, Andrada Larisa
Burz, Claudia Cristina
Bocsan, Ioana Corina
Buzoianu, Anca Dana
author_sort Deac, Andrada Larisa
collection PubMed
description Cardio-oncology is a discipline based on early screening, monitoring, and treating chemotherapy-induced cardiotoxicity. There are many chemotherapeutics known for their cardiac toxic effects, including fluoropyrimidines. Fluoropyrimidine represents the cornerstone of many types of cancer and each year almost two million cancer patients undergo this treatment. Fluoropyrimidine-induced cardiotoxicity can be manifested in several forms, from angina pectoris to sudden death. This paper is a review of how the cardiotoxicity of fluoropyrimidines is presented, the mechanisms of its occurrence, its diagnosis, and management.
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spelling pubmed-77697122021-01-11 Fluoropyrimidine-induced cardiotoxicity Deac, Andrada Larisa Burz, Claudia Cristina Bocsan, Ioana Corina Buzoianu, Anca Dana World J Clin Oncol Minireviews Cardio-oncology is a discipline based on early screening, monitoring, and treating chemotherapy-induced cardiotoxicity. There are many chemotherapeutics known for their cardiac toxic effects, including fluoropyrimidines. Fluoropyrimidine represents the cornerstone of many types of cancer and each year almost two million cancer patients undergo this treatment. Fluoropyrimidine-induced cardiotoxicity can be manifested in several forms, from angina pectoris to sudden death. This paper is a review of how the cardiotoxicity of fluoropyrimidines is presented, the mechanisms of its occurrence, its diagnosis, and management. Baishideng Publishing Group Inc 2020-12-24 2020-12-24 /pmc/articles/PMC7769712/ /pubmed/33437663 http://dx.doi.org/10.5306/wjco.v11.i12.1008 Text en ©The Author(s) 2020. Published by Baishideng Publishing Group Inc. All rights reserved. http://creativecommons.org/licenses/by-nc/4.0/ This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial.
spellingShingle Minireviews
Deac, Andrada Larisa
Burz, Claudia Cristina
Bocsan, Ioana Corina
Buzoianu, Anca Dana
Fluoropyrimidine-induced cardiotoxicity
title Fluoropyrimidine-induced cardiotoxicity
title_full Fluoropyrimidine-induced cardiotoxicity
title_fullStr Fluoropyrimidine-induced cardiotoxicity
title_full_unstemmed Fluoropyrimidine-induced cardiotoxicity
title_short Fluoropyrimidine-induced cardiotoxicity
title_sort fluoropyrimidine-induced cardiotoxicity
topic Minireviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769712/
https://www.ncbi.nlm.nih.gov/pubmed/33437663
http://dx.doi.org/10.5306/wjco.v11.i12.1008
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