The Rash, the Weakness, and the Nephritis: Nerve and Kidney Biopsy Findings in Eosinophilic Granulomatosis With Polyangiitis

We present a case of eosinophilic granulomatosis with polyangiitis (EGPA) or Churg-Strauss syndrome in a 66-year Caucasian female who presented with a severe pruritic itch and a progressive upper and lower extremity weakness of unknown duration. The diagnosis of EGPA in this patient remained elusive...

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Detalles Bibliográficos
Autores principales: Ibrahim, Mohd Elmugtaba, Deonarine, Anand, Gore, Payton A, Lewis, Harvey R, Alvarado, Eduardo C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769733/
https://www.ncbi.nlm.nih.gov/pubmed/33391913
http://dx.doi.org/10.7759/cureus.11676
Descripción
Sumario:We present a case of eosinophilic granulomatosis with polyangiitis (EGPA) or Churg-Strauss syndrome in a 66-year Caucasian female who presented with a severe pruritic itch and a progressive upper and lower extremity weakness of unknown duration. The diagnosis of EGPA in this patient remained elusive for an extended period of time due to the absence of respiratory symptoms. In this article, we also discuss the histologic features of EGPA seen in biopsies of the kidney and the nerves and highlight the value they play in diagnosis.

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