The Rash, the Weakness, and the Nephritis: Nerve and Kidney Biopsy Findings in Eosinophilic Granulomatosis With Polyangiitis

We present a case of eosinophilic granulomatosis with polyangiitis (EGPA) or Churg-Strauss syndrome in a 66-year Caucasian female who presented with a severe pruritic itch and a progressive upper and lower extremity weakness of unknown duration. The diagnosis of EGPA in this patient remained elusive...

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Autores principales: Ibrahim, Mohd Elmugtaba, Deonarine, Anand, Gore, Payton A, Lewis, Harvey R, Alvarado, Eduardo C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2020
Materias:
Pathology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769733/
https://www.ncbi.nlm.nih.gov/pubmed/33391913
http://dx.doi.org/10.7759/cureus.11676
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author Ibrahim, Mohd Elmugtaba
Deonarine, Anand
Gore, Payton A
Lewis, Harvey R
Alvarado, Eduardo C
author_facet Ibrahim, Mohd Elmugtaba
Deonarine, Anand
Gore, Payton A
Lewis, Harvey R
Alvarado, Eduardo C
author_sort Ibrahim, Mohd Elmugtaba
collection PubMed
description We present a case of eosinophilic granulomatosis with polyangiitis (EGPA) or Churg-Strauss syndrome in a 66-year Caucasian female who presented with a severe pruritic itch and a progressive upper and lower extremity weakness of unknown duration. The diagnosis of EGPA in this patient remained elusive for an extended period of time due to the absence of respiratory symptoms. In this article, we also discuss the histologic features of EGPA seen in biopsies of the kidney and the nerves and highlight the value they play in diagnosis.
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spelling pubmed-77697332020-12-31 The Rash, the Weakness, and the Nephritis: Nerve and Kidney Biopsy Findings in Eosinophilic Granulomatosis With Polyangiitis Ibrahim, Mohd Elmugtaba Deonarine, Anand Gore, Payton A Lewis, Harvey R Alvarado, Eduardo C Cureus Pathology We present a case of eosinophilic granulomatosis with polyangiitis (EGPA) or Churg-Strauss syndrome in a 66-year Caucasian female who presented with a severe pruritic itch and a progressive upper and lower extremity weakness of unknown duration. The diagnosis of EGPA in this patient remained elusive for an extended period of time due to the absence of respiratory symptoms. In this article, we also discuss the histologic features of EGPA seen in biopsies of the kidney and the nerves and highlight the value they play in diagnosis. Cureus 2020-11-24 /pmc/articles/PMC7769733/ /pubmed/33391913 http://dx.doi.org/10.7759/cureus.11676 Text en Copyright © 2020, Ibrahim et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Ibrahim, Mohd Elmugtaba
Deonarine, Anand
Gore, Payton A
Lewis, Harvey R
Alvarado, Eduardo C
The Rash, the Weakness, and the Nephritis: Nerve and Kidney Biopsy Findings in Eosinophilic Granulomatosis With Polyangiitis
title The Rash, the Weakness, and the Nephritis: Nerve and Kidney Biopsy Findings in Eosinophilic Granulomatosis With Polyangiitis
title_full The Rash, the Weakness, and the Nephritis: Nerve and Kidney Biopsy Findings in Eosinophilic Granulomatosis With Polyangiitis
title_fullStr The Rash, the Weakness, and the Nephritis: Nerve and Kidney Biopsy Findings in Eosinophilic Granulomatosis With Polyangiitis
title_full_unstemmed The Rash, the Weakness, and the Nephritis: Nerve and Kidney Biopsy Findings in Eosinophilic Granulomatosis With Polyangiitis
title_short The Rash, the Weakness, and the Nephritis: Nerve and Kidney Biopsy Findings in Eosinophilic Granulomatosis With Polyangiitis
title_sort rash, the weakness, and the nephritis: nerve and kidney biopsy findings in eosinophilic granulomatosis with polyangiitis
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769733/
https://www.ncbi.nlm.nih.gov/pubmed/33391913
http://dx.doi.org/10.7759/cureus.11676
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