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Sevoflurane-Induced Neuroapoptosis in Rat Dentate Gyrus Is Activated by Autophagy Through NF-κB Signaling on the Late-Stage Progenitor Granule Cells

OBJECTIVE: The mechanisms by which exposure of the late-stage progenitor cells to the anesthesia sevoflurane alters their differentiation are not known. We seek to query whether the effects of sevoflurane on late-stage progenitor cells might be regulated by apoptosis and/or autophagy. METHODS: To ad...

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Detalles Bibliográficos
Autores principales: Tong, Dongyi, Ma, Zhongliang, Su, Peng, Wang, Shuai, Xu, Ying, Zhang, Li Min, Wu, Ziyi, Liu, Kun, Zhao, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769878/
https://www.ncbi.nlm.nih.gov/pubmed/33384584
http://dx.doi.org/10.3389/fncel.2020.590577