Anisodamine Maintains the Stability of Intervertebral Disc Tissue by Inhibiting the Senescence of Nucleus Pulposus Cells and Degradation of Extracellular Matrix via Interleukin-6/Janus Kinases/Signal Transducer and Activator of Transcription 3 Pathway

Objectives: Anisodamine (ANI) has been used to treat a variety of diseases. However, the study of ANI in intervertebral disc degeneration (IVDD) is unclear. This study investigated the effects of ANI on degenerative nucleus pulposus cells (NPCs) and IVDD rats, and its possible mechanisms. Methods: H...

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Detalles Bibliográficos
Autores principales: Tang, Ning, Dong, Yulei, Chen, Chong, Zhao, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769940/
https://www.ncbi.nlm.nih.gov/pubmed/33384595
http://dx.doi.org/10.3389/fphar.2020.519172

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769940/
https://www.ncbi.nlm.nih.gov/pubmed/33384595
http://dx.doi.org/10.3389/fphar.2020.519172

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