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In silico discovery of antigenic proteins and epitopes of SARS-CoV-2 for the development of a vaccine or a diagnostic approach for COVID-19

In the genome of SARS-CoV-2, the 5′-terminus encodes a polyprotein, which is further cleaved into 15 non-structural proteins whereas the 3′ terminus encodes four structural proteins and eight accessory proteins. Among these 27 proteins, the present study aimed to discover likely antigenic proteins a...

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Detalles Bibliográficos
Autores principales: Can, Hüseyin, Köseoğlu, Ahmet Efe, Erkunt Alak, Sedef, Güvendi, Mervenur, Döşkaya, Mert, Karakavuk, Muhammet, Gürüz, Adnan Yüksel, Ün, Cemal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769971/
https://www.ncbi.nlm.nih.gov/pubmed/33372181
http://dx.doi.org/10.1038/s41598-020-79645-9