Comprehensive phenotyping revealed transient startle response reduction and histopathological gadolinium localization to perineuronal nets after gadodiamide administration in rats

Gadolinium based contrast agents (GBCAs) are widely used in clinical MRI since the mid-1980s. Recently, concerns have been raised that trace amounts of Gadolinium (Gd), detected in brains even long time after GBCA application, may cause yet unrecognized clinical consequences. We therefore assessed t...

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Detalles Bibliográficos
Autores principales: Habermeyer, Johanna, Boyken, Janina, Harrer, Julia, Canneva, Fabio, Ratz, Veronika, Moceri, Sandra, Admard, Jakob, Casadei, Nicolas, Jost, Gregor, Bäuerle, Tobias, Frenzel, Thomas, Schmitz, Christoph, Schütz, Gunnar, Pietsch, Hubertus, von Hörsten, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7769977/
https://www.ncbi.nlm.nih.gov/pubmed/33372182
http://dx.doi.org/10.1038/s41598-020-79374-z

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