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Progression of Cerebellar Atrophy in Spinocerebellar Ataxia Type 2 Gene Carriers: A Longitudinal MRI Study in Preclinical and Early Disease Stages
Spinocerebellar ataxias type 2 (SCA2) is an autosomal dominant inherited disease caused by expanded trinucleotide repeats (≥32 CAG) within the coding region of ATXN2 gene. Age of disease onset primarily depends on the length of the expanded region. The majority of subjects carrying the mutation rema...
Autores principales: | Nigri, Anna, Sarro, Lidia, Mongelli, Alessia, Pinardi, Chiara, Porcu, Luca, Castaldo, Anna, Ferraro, Stefania, Grisoli, Marina, Bruzzone, Maria Grazia, Gellera, Cinzia, Taroni, Franco, Mariotti, Caterina, Nanetti, Lorenzo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770103/ https://www.ncbi.nlm.nih.gov/pubmed/33384659 http://dx.doi.org/10.3389/fneur.2020.616419 |
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