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NRF2 -617 C/A Polymorphism Impacts Proinflammatory Cytokine Levels, Survival, and Transplant-Related Mortality After Hematopoietic Stem Cell Transplantation in Adult Patients Receiving Busulfan-Based Conditioning Regimens

Busulfan (BU) is widely used in conditioning regimens prior to hematopoietic stem cell transplantation (HSCT). The exposure-escalated BU directed by therapeutic drug monitoring (TDM) is extremely necessary for the patients with high-risk hematologic malignancies in order to diminish relapse, but it...

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Detalles Bibliográficos
Autores principales: Huang, Jingjing, Hao, Chenxia, Li, Ziwei, Wang, Ling, Jiang, Jieling, Tang, Wei, Wang, Lining, Zhang, Weixia, Hu, Jiong, Yang, Wanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770105/
https://www.ncbi.nlm.nih.gov/pubmed/33384597
http://dx.doi.org/10.3389/fphar.2020.563321