Abnormal podocyte TRPML1 channel activity and exosome release in mice with podocyte-specific Asah1 gene deletion

Podocytopathy and associated nephrotic syndrome (NS) have been reported in a knockout mouse strain (Asah1(fl/fl)/Podo(Cre)) with a podocyte-specific deletion of α subunit (the main catalytic subunit) of acid ceramidase (Ac). However, the pathogenesis of podocytopathy of these mice remains unknown. T...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Guangbi, Huang, Dandan, Bhat, Owais M., Poklis, Justin L., Zhang, Aolin, Zou, Yao, Kidd, Jason, Gehr, Todd W.B., Li, Pin-Lan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770122/
https://www.ncbi.nlm.nih.gov/pubmed/33221496
http://dx.doi.org/10.1016/j.bbalip.2020.158856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770122/
https://www.ncbi.nlm.nih.gov/pubmed/33221496
http://dx.doi.org/10.1016/j.bbalip.2020.158856

Ejemplares similares