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Abnormal podocyte TRPML1 channel activity and exosome release in mice with podocyte-specific Asah1 gene deletion
Podocytopathy and associated nephrotic syndrome (NS) have been reported in a knockout mouse strain (Asah1(fl/fl)/Podo(Cre)) with a podocyte-specific deletion of α subunit (the main catalytic subunit) of acid ceramidase (Ac). However, the pathogenesis of podocytopathy of these mice remains unknown. T...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770122/ https://www.ncbi.nlm.nih.gov/pubmed/33221496 http://dx.doi.org/10.1016/j.bbalip.2020.158856 |