Cargando…

Unraveling Early Signs of Navigational Impairment in APPswe/PS1dE9 Mice Using Morris Water Maze

Mild behavioral deficits, which are part of normal aging, can be early indicators of an impending Alzheimer's disease. Using the APPswe/PS1dE9 (APP/PS1) mouse model of Alzheimer's disease, we utilized the Morris water maze spatial learning paradigm to systematically evaluate mild behaviora...

Descripción completa

Detalles Bibliográficos
Autor principal:	Karunakaran, Smitha
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770143/ https://www.ncbi.nlm.nih.gov/pubmed/33384577 http://dx.doi.org/10.3389/fnins.2020.568200

Ejemplares similares

Morris Water Maze Experiment
por: Nunez, Joseph
Publicado: (2008)

Early β adrenoceptor dependent time window for fear memory persistence in APPswe/PS1dE9 mice
por: Karunakaran, Smitha
Publicado: (2021)

Morris Water Maze Test for Learning and Memory Deficits in Alzheimer's Disease Model Mice
por: Bromley-Brits, Kelley, et al.
Publicado: (2011)

Comparison of different protocols of Morris water maze in cognitive impairment with heart failure
por: Lu, Ziwen, et al.
Publicado: (2020)

The Protective Effect of Vanadium on Cognitive Impairment and the Neuropathology of Alzheimer’s Disease in APPSwe/PS1dE9 Mice
por: He, Zhijun, et al.
Publicado: (2020)

Distinct epigenetic and gene expression changes in rat hippocampal neurons after Morris water maze training
por: Carter, Sylvia D., et al.
Publicado: (2015)

Sex differences in the IntelliCage and the Morris water maze in the APP/PS1 mouse model of amyloidosis
por: Mifflin, Marc A., et al.
Publicado: (2021)

An old test for new neurons: refining the Morris water maze to study the functional relevance of adult hippocampal neurogenesis
por: Garthe, Alexander, et al.
Publicado: (2013)

Morris Water Maze and Contextual Fear Conditioning Tasks to Evaluate Cognitive Functions Associated With Adult Hippocampal Neurogenesis
por: Hernández-Mercado, Karina, et al.
Publicado: (2022)

Memory-Enhancing Activity of Palmatine in Mice Using Elevated Plus Maze and Morris Water Maze
por: Dhingra, Dinesh, et al.
Publicado: (2012)

MoNETA: massive parallel application of biological models navigating through virtual Morris water maze and beyond
por: Gorchetchnikov, Anatoli, et al.
Publicado: (2011)

A new automatic method for tracking rats in the Morris water maze
por: Forero, Manuel G., et al.
Publicado: (2023)

7-NI and ODQ Disturbs Memory in the Elevated Plus Maze, Morris Water Maze, and Radial Arm Maze Tests in Mice
por: Mutlu, Oguz, et al.
Publicado: (2015)

Longitudinal Assessment of Working Memory Performance in the APPswe/PSEN1dE9 Mouse Model of Alzheimer’s Disease Using an Automated Figure-8-Maze
por: van Heusden, Fran C., et al.
Publicado: (2021)

Divergence in Morris Water Maze-Based Cognitive Performance under Chronic Stress Is Associated with the Hippocampal Whole Transcriptomic Modification in Mice
por: Jung, Seung H., et al.
Publicado: (2017)

Evaluation of the Activity of Choline Acetyltransferase From Different Synaptosomal Fractions at the Distinct Stages of Spatial Learning in the Morris Water Maze
por: Storozheva, Zinaida I., et al.
Publicado: (2021)

Molecular mechanisms for the destabilization and restabilization of reactivated spatial memory in the Morris water maze
por: Kim, Ryang, et al.
Publicado: (2011)

Using the Morris Water Maze to Assess Spatial Learning and Memory in Weanling Mice
por: Barnhart, Christopher D., et al.
Publicado: (2015)

Genes associated with cognitive performance in the Morris water maze: an RNA-seq study
por: Reshetnikov, Vasiliy V., et al.
Publicado: (2020)

Search strategy analysis of Tg4-42 Alzheimer Mice in the Morris Water Maze reveals early spatial navigation deficits
por: Curdt, Nadine, et al.
Publicado: (2022)

YXQN Reduces Alzheimer’s Disease-Like Pathology and Cognitive Decline in APPswePS1dE9 Transgenic Mice
por: Wang, Xiaowan, et al.
Publicado: (2017)

Searching for cognitive enhancement in the Morris water maze: better and worse performance in D‐amino acid oxidase knockout (Dao (−/−)) mice
por: Pritchett, David, et al.
Publicado: (2016)

Recognition of early stage thigmotaxis in Morris water maze test with convolutional neural network
por: Higaki, Akinori, et al.
Publicado: (2018)

A generalised framework for detailed classification of swimming paths inside the Morris Water Maze
por: Vouros, Avgoustinos, et al.
Publicado: (2018)

Accelerated Failure Time Survival Model to Analyze Morris Water Maze Latency Data
por: Andersen, Clark R., et al.
Publicado: (2021)

Morris water maze: a versatile and pertinent tool for assessing spatial learning and memory
por: Othman, Muhammad Zulfadhli, et al.
Publicado: (2022)

A Comparative Study of the Impact of NO-Related Agents on MK-801- or Scopolamine-Induced Cognitive Impairments in the Morris Water Maze
por: Cieślik, Paulina, et al.
Publicado: (2023)

Mitochondrial dynamics changes with age in an APPsw/PS1dE9 mouse model of Alzheimer’s disease
por: Xu, Lin-Lin, et al.
Publicado: (2017)

Search Strategy Analysis of 5xFAD Alzheimer Mice in the Morris Water Maze Reveals Sex- and Age-Specific Spatial Navigation Deficits
por: Sánchez, Carolina Quintanilla, et al.
Publicado: (2023)

Effects of training in the Morris water maze on the spatial learning acquisition and VAChT expression in male rats
por: Hosseini-Sharifabad, A., et al.
Publicado: (2011)

Detailed classification of swimming paths in the Morris Water Maze: multiple strategies within one trial
por: Gehring, Tiago V., et al.
Publicado: (2015)

Predicting outcome of Morris water maze test in vascular dementia mouse model with deep learning
por: Higaki, Akinori, et al.
Publicado: (2018)

Dynamic Evaluation Indices in Spatial Learning and Memory of Rat Vascular Dementia in the Morris Water Maze
por: Yuan, Ze, et al.
Publicado: (2019)

Effects of low-dose lipopolysaccharide and age on spatial learning in different Morris water maze protocols
por: Kupferschmid, Barbara J, et al.
Publicado: (2017)

A new statistical method to analyze Morris Water Maze data using Dirichlet distribution
por: Maugard, Marianne, et al.
Publicado: (2019)

Mechanisms Mediating the Protective Effects of Eicosapentaenoic Acid in Brain of the APPswePS1dE9 Alzheimer's Mouse Model
por: Yavari, Mahsa, et al.
Publicado: (2022)

5-HTT Deficiency Affects Neuroplasticity and Increases Stress Sensitivity Resulting in Altered Spatial Learning Performance in the Morris Water Maze but Not in the Barnes Maze
por: Karabeg, Margherita M., et al.
Publicado: (2013)

The effects of Gouqi extracts on Morris maze learning in the APP/PS1 double transgenic mouse model of Alzheimer’s disease
por: ZHANG, QIANLIN, et al.
Publicado: (2013)

PT671. The effects and mechanism of action of galangin on spatial memory in the Morris water maze test in rats
por: Kilic, Fatma Sultan, et al.
Publicado: (2016)

Identifying the appropriate time for deep brain stimulation to achieve spatial memory improvement on the Morris water maze
por: Jeong, Da Un, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_4fb39oaquheqe6hi29lpn27kuj