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Highly Sensitive Flow Cytometric Detection of Residual B-Cells After Rituximab in Anti-Neutrophil Cytoplasmic Antibodies-Associated Vasculitis Patients

BACKGROUND: B-cell depletion with rituximab (RTX) is an effective treatment for anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) patients. Nevertheless, relapses are frequent after RTX, often preceded by B-cell repopulation suggesting that residual autoreactive B-cells persi...

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Detalles Bibliográficos
Autores principales: van Dam, Laura S., Oskam, Jelle M., Kamerling, Sylvia W. A., Arends, Eline J., Bredewold, O. W., Berkowska, Magdalena A., van Dongen, Jacques J. M., Rabelink, Ton J., van Kooten, Cees, Teng, Y. K. Onno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770159/
https://www.ncbi.nlm.nih.gov/pubmed/33384685
http://dx.doi.org/10.3389/fimmu.2020.566732