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Highly Sensitive Flow Cytometric Detection of Residual B-Cells After Rituximab in Anti-Neutrophil Cytoplasmic Antibodies-Associated Vasculitis Patients
BACKGROUND: B-cell depletion with rituximab (RTX) is an effective treatment for anti-neutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV) patients. Nevertheless, relapses are frequent after RTX, often preceded by B-cell repopulation suggesting that residual autoreactive B-cells persi...
Autores principales: | van Dam, Laura S., Oskam, Jelle M., Kamerling, Sylvia W. A., Arends, Eline J., Bredewold, O. W., Berkowska, Magdalena A., van Dongen, Jacques J. M., Rabelink, Ton J., van Kooten, Cees, Teng, Y. K. Onno |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770159/ https://www.ncbi.nlm.nih.gov/pubmed/33384685 http://dx.doi.org/10.3389/fimmu.2020.566732 |
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