Cargando…

Spatial mapping of collagen content and structure in human intervertebral disk degeneration

Collagen plays a key structural role in both the annulus fibrosus (AF) and nucleus pulposus (NP) of intervertebral disks (IVDs). Changes in collagen content with degeneration suggest a shift from collagen type II to type I within the NP, and the activation of pro‐inflammatory factors is indicative o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zeldin, Lawrence, Mosley, Grace E., Laudier, Damien, Gallate, Zachary S., Gansau, Jennifer, Hoy, Robert C., Poeran, Jashvant, Iatridis, James C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2020
Materias:	Special Issue PSRS Conference 2019
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770200/ https://www.ncbi.nlm.nih.gov/pubmed/33392461 http://dx.doi.org/10.1002/jsp2.1129

Ejemplares similares

Advanced glycation end products cause RAGE‐dependent annulus fibrosus collagen disruption and loss identified using in situ second harmonic generation imaging in mice intervertebral disk in vivo and in organ culture models
por: Hoy, Robert C., et al.
Publicado: (2020)

Effects of suppressing bioavailability of insulin‐like growth factor on age‐associated intervertebral disc degeneration
por: Kritschil, Rebecca, et al.
Publicado: (2020)

Advancing basic and preclinical spine research: Highlights from the ORS PSRS 5th International Spine Research Symposium
por: Smith, Lachlan J., et al.
Publicado: (2020)

Confocal scanning of intervertebral disc cells in 3D: Inside alginate beads and in native microenvironment
por: Hernandez, Paula A., et al.
Publicado: (2020)

Imaging the local biochemical content of native and injured intervertebral disc using Fourier transform infrared microscopy
por: Sloan, Stephen R., et al.
Publicado: (2020)

Galectin‐3 and RAGE differentially control advanced glycation endproduct‐induced collagen damage in murine intervertebral disc organ culture
por: Gallate, Zachary S., et al.
Publicado: (2023)

Canine models of spine disorders
por: Lee, Naomi N., et al.
Publicado: (2020)

Verteporfin treatment controls morphology, phenotype, and global gene expression for cells of the human nucleus pulposus
por: Fearing, Bailey V., et al.
Publicado: (2020)

Age‐related molecular changes in the lumbar dorsal root ganglia of mice: Signs of sensitization, and inflammatory response
por: Vincent, Kathleen, et al.
Publicado: (2020)

Characterization of bovine and canine animal model cartilage endplates and comparison to human cartilage endplate structure, matrix composition, and cell phenotype
por: Lakstins, Katherine, et al.
Publicado: (2020)

Spinal Cord Sensitization and Spinal Inflammation from an In Vivo Rat Endplate Injury Associated with Painful Intervertebral Disc Degeneration
por: Lai, Alon, et al.
Publicado: (2023)

Lumbar endplate microfracture injury induces Modic-like changes, intervertebral disc degeneration and spinal cord sensitization – An In Vivo Rat Model
por: Wang, Dalin, et al.
Publicado: (2023)

Dietary advanced glycation end-product consumption leads to mechanical stiffening of murine intervertebral discs
por: Krishnamoorthy, Divya, et al.
Publicado: (2018)

Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice
por: Zhang, Changli, et al.
Publicado: (2019)

Antioxidative nanofullerol prevents intervertebral disk degeneration
por: Yang, Xinlin, et al.
Publicado: (2014)

Mechanobiology of MicroRNAs in Intervertebral Disk Degeneration
por: Supra, Rajiv, et al.
Publicado: (2023)

Dietary polyphenols as a safe and novel intervention for modulating pain associated with intervertebral disc degeneration in an in-vivo rat model
por: Lai, Alon, et al.
Publicado: (2019)

Males and females exhibit distinct relationships between intervertebral disc degeneration and pain in a rat model
por: Mosley, Grace E., et al.
Publicado: (2020)

Correction: Dietary polyphenols as a safe and novel intervention for modulating pain associated with intervertebral disc degeneration in an in-vivo rat model
por: Lai, Alon, et al.
Publicado: (2019)

Inflammatory Mediators in Intervertebral Disk Degeneration and Discogenic Pain
por: Wuertz, Karin, et al.
Publicado: (2013)

Circular RNAs in compression-induced intervertebral disk degeneration
por: Chen, Ximiao, et al.
Publicado: (2020)

Intervertebral Disk Degeneration: The Microenvironment and Tissue Engineering Strategies
por: Dou, Yiming, et al.
Publicado: (2021)

Cytokine Imbalance as a Biomarker of Intervertebral Disk Degeneration
por: Shnayder, Natalia A., et al.
Publicado: (2023)

Development of a standardized histopathology scoring system for intervertebral disc degeneration and regeneration in rabbit models‐An initiative of the ORSspine section
por: Gullbrand, Sarah E., et al.
Publicado: (2021)

FOXO are required for intervertebral disk homeostasis during aging and their deficiency promotes disk degeneration
por: Alvarez‐Garcia, Oscar, et al.
Publicado: (2018)

Combined Anti-Inflammatory and Anti-AGE Drug Treatments Have a Protective Effect on Intervertebral Discs in Mice with Diabetes
por: Illien-Junger, Svenja, et al.
Publicado: (2013)

Moderately Degenerated Human Intervertebral Disks Exhibit a Less Geometrically Specific Collagen Fiber Orientation Distribution
por: Dittmar, Roman, et al.
Publicado: (2015)

Development of a standardized histopathology scoring system for intervertebral disc degeneration in rat models: An initiative of the ORS spine section
por: Lai, Alon, et al.
Publicado: (2021)

Mechanisms of Intervertebral Disk Degeneration/Injury and Pain: A Review
por: Ito, Keita, et al.
Publicado: (2013)

BALANCING BIOLOGICAL AND BIOMECHANICAL PERFORMANCE IN INTERVERTEBRAL DISC REPAIR: A SYSTEMATIC REVIEW OF INJECTABLE CELL DELIVERY BIOMATERIALS
por: Panebianco, C.J., et al.
Publicado: (2020)

Anterior Limbus Vertebra and Intervertebral Disk Degeneration in Japanese Collegiate Gymnasts
por: Koyama, Koji, et al.
Publicado: (2013)

Association Between VDR FokI Polymorphism and Intervertebral Disk Degeneration
por: Zhao, Jian, et al.
Publicado: (2015)

Expression of metalloproteinases and their inhibitors in degenerated and extruded intervertebral disks in chondrodystrophic dogs
por: ISHINO, Hirokazu, et al.
Publicado: (2021)

Influence of Age and Gender on Intervertebral Disk Degeneration and Height in the Thoracolumbar Spine
por: Machino, Masaaki, et al.
Publicado: (2021)

Effect of percutaneous nucleoplasty with coblation on phospholipase A2 activity in the intervertebral disks of an animal model of intervertebral disk degeneration: a randomized controlled trial
por: Ren, Dajiang, et al.
Publicado: (2015)

Intervertebral Disk Degeneration in Rabbits: Histomorphometric and Histomorphological Effects of Aloe Vera Gel
por: Akinola, Busuyi Kolade, et al.
Publicado: (2020)

Current Progress in the Endogenous Repair of Intervertebral Disk Degeneration Based on Progenitor Cells
por: Zhang, Yanbin, et al.
Publicado: (2021)

MiR-206 improves intervertebral disk degeneration by targeting GJA1
por: Zhou, Peng, et al.
Publicado: (2022)

Does Calcium Phosphate Cement Kyphoplasty Cause Intervertebral Disk Degeneration in Adolescents?
por: Tschauner, Sebastian, et al.
Publicado: (2022)

The first disk-based custodial storage for the ALICE experiment
por: Ahn, Sang Un
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_si2grvnf52h3i46pp1oc825asi