Presynaptic vesicular accumulation is required for antipsychotic efficacy in psychotic-like rats

BACKGROUND: The therapeutic effects of antipsychotic drugs (APDs) are mainly attributed to their postsynaptic inhibitory functions on the dopamine D2 receptor, which, however, cannot explain the delayed onset of full therapeutic efficacy. It was previously shown that APDs accumulate in presynaptic v...

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Detalles Bibliográficos
Autores principales: Uzuneser, Taygun C, Weiss, Eva-Maria, Dahlmanns, Jana, Kalinichenko, Liubov S, Amato, Davide, Kornhuber, Johannes, Alzheimer, Christian, Hellmann, Jan, Kaindl, Jonas, Hübner, Harald, Löber, Stefan, Gmeiner, Peter, Grömer, Teja W, Müller, Christian P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770212/
https://www.ncbi.nlm.nih.gov/pubmed/33274688
http://dx.doi.org/10.1177/0269881120965908

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770212/
https://www.ncbi.nlm.nih.gov/pubmed/33274688
http://dx.doi.org/10.1177/0269881120965908

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