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Repurposing FDA Approved Drugs as JNK3 Inhibitor for Prevention of Neuroinflammation Induced by MCAO in Rats

BACKGROUND: Stress-associated kinases are considered major pathological mediators in several incurable neurological disorders. Importantly, among these stress kinases, the c-Jun NH2-terminal kinase (JNK) has been linked to numerous neuropathological conditions, including oxidative stress, neuroinfla...

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Detalles Bibliográficos
Autores principales: Zulfiqar, Zikra, Shah, Fawad Ali, Shafique, Shagufta, Alattar, Abdullah, Ali, Tahir, Alvi, Arooj Mohsin, Rashid, Sajid, Li, Shupeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770337/
https://www.ncbi.nlm.nih.gov/pubmed/33384558
http://dx.doi.org/10.2147/JIR.S284471