Single-cell RNA Sequencing in Immunology

The complex immune system is involved in multiple pathological processes. Single-cell RNA sequencing (scRNA-seq) is able to analyze complex cell mixtures correct to a single cell and single molecule, thus is qualified to analyze immune reactions in several diseases. In recent years, scRNA-seq has be...

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Detalles Bibliográficos
Autores principales: Cao, Yirui, Qiu, Yue, Tu, Guowei, Yang, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770633/
https://www.ncbi.nlm.nih.gov/pubmed/33414678
http://dx.doi.org/10.2174/1389202921999201020203249
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author Cao, Yirui
Qiu, Yue
Tu, Guowei
Yang, Cheng
author_facet Cao, Yirui
Qiu, Yue
Tu, Guowei
Yang, Cheng
author_sort Cao, Yirui
collection PubMed
description The complex immune system is involved in multiple pathological processes. Single-cell RNA sequencing (scRNA-seq) is able to analyze complex cell mixtures correct to a single cell and single molecule, thus is qualified to analyze immune reactions in several diseases. In recent years, scRNA-seq has been applied in many researching fields and has presented many innovative results. In this review, we intend to provide an overview of single-cell RNA sequencing applications in immunology and a prospect of future directions.
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spelling pubmed-77706332021-06-01 Single-cell RNA Sequencing in Immunology Cao, Yirui Qiu, Yue Tu, Guowei Yang, Cheng Curr Genomics Article The complex immune system is involved in multiple pathological processes. Single-cell RNA sequencing (scRNA-seq) is able to analyze complex cell mixtures correct to a single cell and single molecule, thus is qualified to analyze immune reactions in several diseases. In recent years, scRNA-seq has been applied in many researching fields and has presented many innovative results. In this review, we intend to provide an overview of single-cell RNA sequencing applications in immunology and a prospect of future directions. Bentham Science Publishers 2020-12 2020-12 /pmc/articles/PMC7770633/ /pubmed/33414678 http://dx.doi.org/10.2174/1389202921999201020203249 Text en © 2020 Bentham Science Publishers https://creativecommons.org/licenses/by-nc/4.0/legalcode This is an open access article licensed under the terms of the Creative Commons Attribution-Non-Commercial 4.0 International Public License (CC BY-NC 4.0) (https://creativecommons.org/licenses/by-nc/4.0/legalcode), which permits unrestricted, non-commercial use, distribution and reproduction in any medium, provided the work is properly cited.
spellingShingle Article
Cao, Yirui
Qiu, Yue
Tu, Guowei
Yang, Cheng
Single-cell RNA Sequencing in Immunology
title Single-cell RNA Sequencing in Immunology
title_full Single-cell RNA Sequencing in Immunology
title_fullStr Single-cell RNA Sequencing in Immunology
title_full_unstemmed Single-cell RNA Sequencing in Immunology
title_short Single-cell RNA Sequencing in Immunology
title_sort single-cell rna sequencing in immunology
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770633/
https://www.ncbi.nlm.nih.gov/pubmed/33414678
http://dx.doi.org/10.2174/1389202921999201020203249
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