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Antitubercular and Antiparasitic 2-Nitroimidazopyrazinones with Improved Potency and Solubility
[Image: see text] Following the approval of delamanid and pretomanid as new drugs to treat drug-resistant tuberculosis, there is now a renewed interest in bicyclic nitroimidazole scaffolds as a source of therapeutics against infectious diseases. We recently described a nitroimidazopyrazinone bicycli...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Chemical Society
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770830/ https://www.ncbi.nlm.nih.gov/pubmed/33151678 http://dx.doi.org/10.1021/acs.jmedchem.0c01372 |