NKT Cells Join the Two Step for Inflammasome-Independent IL-1β Release

The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, but pathogens often evade this pathway. In this issue Donado et al. (2020) describe an alternative, two-cell model, to instruct inflammasome-independent IL-1β releas...

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Detalles Bibliográficos
Autores principales: Bezbradica, Jelena S., Joyce, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770951/
https://www.ncbi.nlm.nih.gov/pubmed/32268100
http://dx.doi.org/10.1016/j.celrep.2020.03.045
Descripción
Sumario:The cytokine interleukin-1β (IL-1β) is critical for antimicrobial defenses; the inflammasome pathway typically controls IL-1β release, but pathogens often evade this pathway. In this issue Donado et al. (2020) describe an alternative, two-cell model, to instruct inflammasome-independent IL-1β release.

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