Intestinal stem cell-derived enteroids from morbidly obese patients preserve obesity-related phenotypes: Elevated glucose absorption and gluconeogenesis

OBJECTIVE: The mechanisms behind the efficacy of bariatric surgery (BS) for treating obesity and type 2 diabetes, particularly with respect to the influence of the small bowel, remain poorly understood. In vitro and animal models are suboptimal with respect to their ability to replicate the human in...

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Detalles Bibliográficos
Autores principales: Hasan, Nesrin M., Johnson, Kelli F., Yin, Jianyi, Baetz, Nicholas W., Fayad, Lea, Sherman, Vadim, Blutt, Sarah E., Estes, Mary K., Kumbhari, Vivek, Zachos, Nicholas C., Kovbasnjuk, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770968/
https://www.ncbi.nlm.nih.gov/pubmed/33246140
http://dx.doi.org/10.1016/j.molmet.2020.101129

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