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Characterization of viral insulins reveals white adipose tissue-specific effects in mice

OBJECTIVE: Members of the insulin/insulin-like growth factor (IGF) superfamily are well conserved across the evolutionary tree. We recently showed that four viruses in the Iridoviridae family possess genes that encode proteins highly homologous to human insulin/IGF-1. Using chemically synthesized si...

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Detalles Bibliográficos
Autores principales: Chrudinová, Martina, Moreau, François, Noh, Hye Lim, Páníková, Terezie, Žáková, Lenka, Friedline, Randall H., Valenzuela, Francisco A., Kim, Jason K., Jiráček, Jiří, Kahn, C. Ronald, Altindis, Emrah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7770979/
https://www.ncbi.nlm.nih.gov/pubmed/33220491
http://dx.doi.org/10.1016/j.molmet.2020.101121