Efficacy of commercial products on nursery pig growth performance fed diets with fumonisin contaminated corn

Two experiments were conducted to determine the efficacy of various commercial products on growth performance of nursery pigs fed diets high in fumonisin. In experiment 1, 350 pigs (241 × 600; DNA, Columbus, NE; initially 9.9 kg) were used with five pigs per pen and 14 replicates per treatment. After weaning, pigs were fed common diets for 21 d before the experiment started. The five dietary treatments consisted of a positive control (low fumonisin), a negative control (60 mg/kg of fumonisin B1 + B2 in complete diet), and the negative control with one of three products (0.3% of Kallsil Dry, Kemin Industries Inc., Des Moines, IA; 0.3% of Feed Aid Wide Spectrum, NutriQuest, Mason City, IA; 0.17% of Biofix Select Pro, Biomin America Inc., Overland Park, KS). Diets were fed in mash form for 14 d and followed with a low fumonisin diet for 13 d. For the 14-d treatment period, pigs fed the positive control diet and Biofix Select Pro had greater (P < 0.05) average daily gain (ADG), average daily feed intake (ADFI), and gain:feed (G:F) compared to those fed the high fumonisin negative control, or high fumonisin diets with Kallsil Dry or Feed Aid Wide Spectrum. Serum sphinganine to sphingosine ratios (SA:SO) were greater (P < 0.05) in all pigs fed high fumonisin diets compared to the positive control. In experiment 2, 300 pigs (241 × 600; DNA; initially 10.4 kg) were used. Procedures were similar to experiment 1 except there were 12 replicate pens per treatment, high fumonisin diets contained 30 mg/kg fumonisin, and experimental diets were fed for 28 d. Similar to experiment 1, pigs fed the positive control diet and treatment with Biofix Select Pro had greater (P < 0.05) ADG and G:F, and lower (P < 0.05) serum SA:SO compared to pigs fed the high fumonisin negative control, or high fumonisin diets with Kallsil Dry or Feed Aid Wide Spectrum. In summary, pigs fed diets containing 60 mg/kg of fumonisin for 14 d or 30 mg/kg of fumonisin for 28 d had poorer ADG and G:F and greater serum SA:SO compared to pigs fed a diet with less than 5 mg/kg of fumonisin. Adding Biofix Select Pro to diets appeared to mitigate the negative effects of high fumonisin concentrations, while Kallsil Dry and Feed Aid Wide Spectrum did not.