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Help or hindrance? The evolutionary impact of whole‐genome duplication on immunogenetic diversity and parasite load
Whole‐genome duplication (WGD) events occur in all kingdoms and have been hypothesized to promote adaptability. WGDs identified in the early history of vertebrates, teleosts, and angiosperms have been linked to the large‐scale diversification of these lineages. However, the mechanics and full outcom...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771170/ https://www.ncbi.nlm.nih.gov/pubmed/33391693 http://dx.doi.org/10.1002/ece3.6987 |
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author | Bell, Ellen A. Cable, Jo Oliveira, Claudio Richardson, David S. Yant, Levi Taylor, Martin I. |
author_facet | Bell, Ellen A. Cable, Jo Oliveira, Claudio Richardson, David S. Yant, Levi Taylor, Martin I. |
author_sort | Bell, Ellen A. |
collection | PubMed |
description | Whole‐genome duplication (WGD) events occur in all kingdoms and have been hypothesized to promote adaptability. WGDs identified in the early history of vertebrates, teleosts, and angiosperms have been linked to the large‐scale diversification of these lineages. However, the mechanics and full outcomes of WGD regarding potential evolutionary impacts remain a topic of debate. The Corydoradinae are a diverse subfamily of Neotropical catfishes with over 170 species described and a history of WGDs. They are divided into nine mtDNA lineages, with species coexisting in sympatric—and often mimetic—communities containing representatives of two or more of the nine lineages. Given their similar life histories, coexisting species of Corydoras might be exposed to similar parasite loads and because of their different histories of WGD and genome size they provide a powerful system for investigating the impacts of WGD on immune diversity and function in an animal system. Here, we compared parasite counts and the diversity of the immune‐related toll‐like receptors (TLR) in two coexisting species of Corydoras catfish (C. maculifer and C. araguaiaensis), one diploid and one putative tetraploid. In the putative tetraploid C. araguaiaensis, we found significantly lower numbers of parasites and significantly higher diversity (measured by both synonymous and nonsynonymous SNP counts) in two TLR genes than in the diploid C. maculifer. These results provide insight into how WGD may impact evolution, in this case by providing greater immunogenetic diversity. |
format | Online Article Text |
id | pubmed-7771170 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-77711702020-12-31 Help or hindrance? The evolutionary impact of whole‐genome duplication on immunogenetic diversity and parasite load Bell, Ellen A. Cable, Jo Oliveira, Claudio Richardson, David S. Yant, Levi Taylor, Martin I. Ecol Evol Original Research Whole‐genome duplication (WGD) events occur in all kingdoms and have been hypothesized to promote adaptability. WGDs identified in the early history of vertebrates, teleosts, and angiosperms have been linked to the large‐scale diversification of these lineages. However, the mechanics and full outcomes of WGD regarding potential evolutionary impacts remain a topic of debate. The Corydoradinae are a diverse subfamily of Neotropical catfishes with over 170 species described and a history of WGDs. They are divided into nine mtDNA lineages, with species coexisting in sympatric—and often mimetic—communities containing representatives of two or more of the nine lineages. Given their similar life histories, coexisting species of Corydoras might be exposed to similar parasite loads and because of their different histories of WGD and genome size they provide a powerful system for investigating the impacts of WGD on immune diversity and function in an animal system. Here, we compared parasite counts and the diversity of the immune‐related toll‐like receptors (TLR) in two coexisting species of Corydoras catfish (C. maculifer and C. araguaiaensis), one diploid and one putative tetraploid. In the putative tetraploid C. araguaiaensis, we found significantly lower numbers of parasites and significantly higher diversity (measured by both synonymous and nonsynonymous SNP counts) in two TLR genes than in the diploid C. maculifer. These results provide insight into how WGD may impact evolution, in this case by providing greater immunogenetic diversity. John Wiley and Sons Inc. 2020-11-22 /pmc/articles/PMC7771170/ /pubmed/33391693 http://dx.doi.org/10.1002/ece3.6987 Text en © 2020 The Authors. Ecology and Evolution published by John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Research Bell, Ellen A. Cable, Jo Oliveira, Claudio Richardson, David S. Yant, Levi Taylor, Martin I. Help or hindrance? The evolutionary impact of whole‐genome duplication on immunogenetic diversity and parasite load |
title | Help or hindrance? The evolutionary impact of whole‐genome duplication on immunogenetic diversity and parasite load |
title_full | Help or hindrance? The evolutionary impact of whole‐genome duplication on immunogenetic diversity and parasite load |
title_fullStr | Help or hindrance? The evolutionary impact of whole‐genome duplication on immunogenetic diversity and parasite load |
title_full_unstemmed | Help or hindrance? The evolutionary impact of whole‐genome duplication on immunogenetic diversity and parasite load |
title_short | Help or hindrance? The evolutionary impact of whole‐genome duplication on immunogenetic diversity and parasite load |
title_sort | help or hindrance? the evolutionary impact of whole‐genome duplication on immunogenetic diversity and parasite load |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771170/ https://www.ncbi.nlm.nih.gov/pubmed/33391693 http://dx.doi.org/10.1002/ece3.6987 |
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