PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction

Dendritic cells (DCs) orchestrate the initiation, programming, and regulation of anti-tumor immune responses. Emerging evidence indicates that the tumor microenvironment (TME) induces immune dysfunctional tumor-infiltrating DCs (TIDCs), characterized with both increased intracellular lipid content a...

Descripción completa

Detalles Bibliográficos
Autores principales: Yin, Xiaozhe, Zeng, Wenfeng, Wu, Bowen, Wang, Luoyang, Wang, Zihao, Tian, Hongjian, Wang, Luyao, Jiang, Yunhan, Clay, Ryan, Wei, Xiuli, Qin, Yan, Zhang, Fayun, Zhang, Chunling, Jin, Lingtao, Liang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771208/
https://www.ncbi.nlm.nih.gov/pubmed/33086073
http://dx.doi.org/10.1016/j.celrep.2020.108278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771208/
https://www.ncbi.nlm.nih.gov/pubmed/33086073
http://dx.doi.org/10.1016/j.celrep.2020.108278

Ejemplares similares