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PPARα Inhibition Overcomes Tumor-Derived Exosomal Lipid-Induced Dendritic Cell Dysfunction

Dendritic cells (DCs) orchestrate the initiation, programming, and regulation of anti-tumor immune responses. Emerging evidence indicates that the tumor microenvironment (TME) induces immune dysfunctional tumor-infiltrating DCs (TIDCs), characterized with both increased intracellular lipid content a...

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Detalles Bibliográficos
Autores principales:	Yin, Xiaozhe, Zeng, Wenfeng, Wu, Bowen, Wang, Luoyang, Wang, Zihao, Tian, Hongjian, Wang, Luyao, Jiang, Yunhan, Clay, Ryan, Wei, Xiuli, Qin, Yan, Zhang, Fayun, Zhang, Chunling, Jin, Lingtao, Liang, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771208/ https://www.ncbi.nlm.nih.gov/pubmed/33086073 http://dx.doi.org/10.1016/j.celrep.2020.108278

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