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The SARS-CoV-2 Cytopathic Effect Is Blocked by Lysosome Alkalizing Small Molecules
[Image: see text] Understanding the SARS-CoV-2 virus’ pathways of infection, virus–host–protein interactions, and mechanisms of virus-induced cytopathic effects will greatly aid in the discovery and design of new therapeutics to treat COVID-19. Chloroquine and hydroxychloroquine, extensively explore...
Autores principales: | Gorshkov, Kirill, Chen, Catherine Z., Bostwick, Robert, Rasmussen, Lynn, Tran, Bruce Nguyen, Cheng, Yu-Shan, Xu, Miao, Pradhan, Manisha, Henderson, Mark, Zhu, Wei, Oh, Eunkeu, Susumu, Kimihiro, Wolak, Mason, Shamim, Khalida, Huang, Wenwei, Hu, Xin, Shen, Min, Klumpp-Thomas, Carleen, Itkin, Zina, Shinn, Paul, Carlos de la Torre, Juan, Simeonov, Anton, Michael, Sam G., Hall, Matthew D., Lo, Donald C., Zheng, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2020
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7771250/ https://www.ncbi.nlm.nih.gov/pubmed/33346633 http://dx.doi.org/10.1021/acsinfecdis.0c00349 |
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